Tailored Contract Research Organization
Where empirical evidence
meets predictive computation.
Somnova Research generates high-fidelity in vitro data and uses it to calibrate predictive computational models — turning theoretical abstractions into quantitative predictions for the next generation of sleep and neuro-therapeutics.
- In vitro
- characterization & imaging
- Predictive
- computational modeling
- Phoenix, AZ
- tailored & agile
Capabilities
A full loop from bench to model
We pair rigorous wet-lab characterization with quantitative modeling, so every measurement makes the next prediction sharper.
In Vitro Characterization
Physicochemical profiling of developmental compounds — solubility, stability, and solution behavior — measured under controlled, reproducible conditions.
Learn moreQuantitative Imaging
High-fidelity imaging and image analysis to capture and quantify physical properties and behaviors that conventional assays miss.
Learn morePredictive Modeling
Calibration of proprietary QSPR and machine-learning models against empirical baselines to deliver quantitative, decision-grade predictions.
Learn moreData Cataloging
Structured, versioned datasets and a lightweight LIMS that make empirical results traceable, auditable, and ready to feed model calibration.
Learn moreOur approach
The calibration loop
A disciplined cycle that compounds in value — empirical data calibrates the model, and the model focuses the next experiment.
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01
Measure
Collect baseline empirical data on a target compound's foundational physical properties and solution behaviors in vitro.
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02
Calibrate
Fit and validate predictive models against the empirical baseline, quantifying uncertainty at every step.
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03
Predict
Advance the models from theoretical abstractions to high-fidelity quantitative predictions that guide development.
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04
Refine
Feed predictions back into experimental design — each iteration tightens the model and de-risks the next decision.
Therapeutic focus
Sleep & neuro-therapeutics
Our core program centers on the biology of wakefulness and sleep — including orexin (OX2R) receptor pharmacology — an area where small, well-characterized physical differences can translate into meaningful clinical outcomes.
By grounding computational models in carefully measured empirical data, we help compress the distance between a promising molecule and a confident development decision.
- Compound physicochemical baselines
- Solution-behavior characterization
- Model calibration & validation
About
Tailored research, rigorously done
Somnova Research LLC is a tailored contract research organization based in Phoenix, Arizona. We were founded on a simple conviction: that predictive models are only as good as the empirical evidence beneath them.
We operate at the intersection of the wet lab and the computer — small enough to move quickly, rigorous enough to be trusted with foundational data. Our work emphasizes reproducibility, careful uncertainty quantification, and datasets built to last.
Let's talk about your data.
Whether you need foundational characterization, model calibration, or both — we'd like to hear what you're working on.